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Infectious and noninfectious functions of cGAS
Structure of the complex of chicken STING and human TBK1.
The role of ubiquitination in the RIG-I antiviral signaling pathway
Ubiquitin-mediated activation of TAK1 and IKK in IL-1R/TLR pathways
Welcome to Dr. Zhijian "James" Chen’s Lab at the UT Southwestern Medical Center.
We are broadly interested in mechanisms of signal transduction, namely how a cell communicates with its surroundings and within itself. In particular, we are fascinated by how a cell detects harmful or foreign insults and mounts an appropriate response to restore homeostasis.
Please explore our website to learn more about our people and our research.
5323 Harry Hines Blvd, Dallas, TX 75390
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